César Milstein César Milstein César Milstein shared the Nobel Prize for "pioneering contributions to the theory and techniques of immunology, which were said to lay the basis for advances in medical areas such as cancer treatment and the detection of acquired immune deficiency syndrome (AIDS). In work with his colaureate Georges J. F. Koehler, Milstein developed the techniques for producing monoclonal antibodies, antibodies with a specific affinity for certain sites in the body that might find diseased cells but leave healthy cells intact